Use of nevirapine to reduce MTCT of HIV in a real-life situation
OBJECTIVES
To assess the feasibility, acceptability and cost-effectiveness of te his easy-to-use regimen in a 'real life' situation.
METHODS
The HIVNET012 regimen was implemented in a field setting
After informed consent, HIV-positive women were provided with nevirapine and instructions for use at the onset of labour
Follow-up visits were scheduled at 6 and 14 weeks
Perinatal transmission rate after the intervention was compared with transmission rate before
After informed consent, HIV-positive women were provided with nevirapine and instructions for use at the onset of labour
Follow-up visits were scheduled at 6 and 14 weeks
Perinatal transmission rate after the intervention was compared with transmission rate before
RESULTS
After implementing the nevirapine regimen, the perinatal HIV-1 transmission rate at 14 weeks was 18.1%, similar to the 21.7% before the intervention
These data call for further evaluation of the simple nevirapine regimen in field conditions, and underline the need for alternative strategies.
Results have been published in AIDS. 2003 May 23;17(8):1239-42 and AIDS. 2004 Sep 3;18(13):1854-6.
These data call for further evaluation of the simple nevirapine regimen in field conditions, and underline the need for alternative strategies.
Results have been published in AIDS. 2003 May 23;17(8):1239-42 and AIDS. 2004 Sep 3;18(13):1854-6.
Funding agencies
VLIR
Team
Ann Quaghebeur, Fabian Mwanyumba, Patricia Claeys, Marleen Temmerman;
Partners
Coast Provincial General Hospital, Mombasa, Kenya
Period
January 04, 2001 - September 30, 2003
Project status
Project closed